Mine is Final Fantasy 7
The 1v1 fight with Cloud and Sephiroth where he does the awesomest move "Omnislash"

 

All the of Majoras Mask's Boss's are my favorite each one was just so fun!

 

I don't really have a favorite....but you made me want to play majora's mask again, I haven't played it in a long time >_>

 

^ What my bro said. Was a pain in the ass for the first several times we played.. so lost... Then we figured it out >__> The boss looked like a pain. xD

I rarely play games that have bosses. Though, I can tell you my LEAST favorite boss was the final boss in Fable 3. -.-

 

Portal 2 You vs Wheatly and
James Bond vs The evil guy in Nightfire, on the space station, that is armed with nukes. SO MUCH FUN

 

Touhou.

The battle Vs. Flandre.
Note: I've never played Touhou, so #2 would have to be either SA-X (Metroid Fusion) Or Organization XIII (Kingdom Hearts 2)

 

if you ask me i like the boss battle in Zelda spirit tracks in the water temple and the sand temple.i also i like the boss(well not really a boss)in ace combat zero where you have to take down your wing-mate pixy.i love the ace combat series. mostly ace combat zero and 5

 

Fave boss battle was the first one in the Wind Waker.. it was fun :D

Fave boss though has got to be Glados.. I was sad when i blew her up in portal 1

 

Ganon. Zelda the ocarina of time.
It's the best game ever made.

 

My fave:
Andrew vs. Michael

Andrew used Server Shutdown!
Michael was KOed!

 

Old snake vs Liquid/ocelot/younger ocelot from mgs4 on the ship with the main music from each game playing in the background
Love the metal gear solid games.







IM STILL IN A DREAM, SNAKE EATER!!!!!!